Iranian researchers design smart drug delivery system to control inflammation in acute diseases
Researchers at the Faculty of Veterinary Medicine of Tehran University have designed a smart drug delivery system to control inflammation in chronic and acute diseases.
Dr. Jalil Mehrzad Salakjani, a professor at the Department of Microbiology and Immunology at University of Tehran’s Faculty of Veterinary Medicine, highlighted the importance of the achievement, saying, “Today, chronic inflammatory diseases, like atherosclerosis, have created many problems for humans and animals.”
He added, “Designing, processing and manufacturing biocompatible anti-inflammatory pharmaceutical systems with proper stability and smart control in the body is very important for the treatment of chronic diseases.”
Mehrzad Salakjani said the team of researchers at Tehran University sought to improve the existing drug delivery systems by developing cellular nano-frames in order to control the inflammation of atherosclerosis in human ex vivo and rabbits in vivo.
The lead researcher noted that the loaded medicine, unlike common medicines, targets the upstream inflammatory pathways with anti-inflammatory effects.
He said the biocompatible and anti-inflammatory cellular nanospecies can be used as a potential platform for immunotherapy of chronic inflammatory diseases, especially atherosclerosis in humans.
